PepCyber P~Pep


	About PepCyber：P~Pep

	PepCyber :P~Pep is the largest public database of human protein-protein interactions mediated by phosphoprotein binding domains (PPBDs). Current release: v. 1.2 (May 2010), includes 11,269 records of interactions between 387 PPBD proteins and 1,471 substrate proteins, curated from 4,852 published studies. Please direct questions and comments to help@pepcyber.org.


	References

	Gong, W., Zhou, D., Ren, Y., Wang, Y., Zuo, Z., Shen, Y., Xiao, F., Zhu, Q., Hong, A., Zhou, X., Gao, X and Li, T. (2008) PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains. Nucleic Acids Res , 36 , D679-683. [PubMed] [Full text] Wan, J., Kang, S., Tang, C., Yan, J., Ren, Y., Liu, J., Gao, X., Banerjee, A., Ellis, L.B. and Li, T. (2008) Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res . [PubMed] [Full text]


	Related databases

	BOND (formerly BIND), by Unleashed Informatics. DIP, developed at the University of California Los Angeles. DOMINO, developed at the University of Rome Tor Vergata, Italy. ELM, by Eukaryotic Linear Motif (ELM) consortium. HPRD , developed at Institute of Bioinformatics, Bangalore, India and Johns Hopkins University. Phospho.ELM, by Eukaryotic Linear Motif (ELM) consortium. Scansite, developed at Massachusetts Institute of Technology. STRING, by European Molecular Biology Laboratory (EMBL) and University of Zürich (UniZH)

Please choose from the following options:
PPBD Classes	Read about the 10 PPBD classes, including descriptions about the length, structures, representative instances and reported binding specificity for each PPBD class.
PPBD Proteins	Browse PPBD-containing proteins by their gene symbol or synonym, to get detailed information about these proteins.
Search Interactions	Search PPBD-PPEP interactions by PPBD classes, PPBD protein names or synonyms, accessions in NCBI or Swiss-Prot, PPEP sequences or concerned pathways.
Tutorial	View a demonstration about the structure and utility of this database server.
Glossary	Read explanations of the terms and abbreviations used in the web site.